Immunohistochemical assessment of a unique basal pattern of p53 expression in ulcerative-colitis-associated neoplasia using computer-assisted cytometry

BACKGROUND: The basal pattern of p53 expression, defined as its immunoreactivity confined to the basal half of the glands, is associated with early neoplastic lesions in ulcerative colitis (UC). However, their clinical utility of this finding is limited by the use of “visual estimation” (approximate...

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Bibliographic Details
Main Authors: Kobayashi, Shunsuke, Fujimori, Takahiro, Mitomi, Hiroyuki, Tomita, Shigeki, Ichikawa, Kazuhito, Imura, Johji, Fujii, Shigehiko, Itabashi, Michihiro, Kameoka, Shingo, Igarashi, Yoshinori
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047002/
https://ncbi.nlm.nih.gov/pubmed/24886509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-9-99
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