Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through ET(A) Receptor

The endothelin axis, comprising endothelins (ET-1, ET-2 and ET-3) and their receptors (ET(A)R and ET(B)R), has emerged as relevant player in tumor growth and metastasis. Here, we investigated the involvement of ET-1/ET(A)R axis in chronic lymphocytic leukemia (CLL). CLL cells expressed higher levels...

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Autori principali: Maffei, Rossana, Bulgarelli, Jenny, Fiorcari, Stefania, Martinelli, Silvia, Castelli, Ilaria, Valenti, Vanessa, Rossi, Davide, Bonacorsi, Goretta, Zucchini, Patrizia, Potenza, Leonardo, Vallisa, Daniele, Gattei, Valter, Poeta, Giovanni Del, Forconi, Francesco, Gaidano, Gianluca, Narni, Franco, Luppi, Mario, Marasca, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046988/
https://ncbi.nlm.nih.gov/pubmed/24901342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098818
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