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Structural Insight into the Tetramerization of an Iterative Ketoreductase SiaM through Aromatic Residues in the Interfaces

In the biosynthesis of polyketides, ketoreductases (KRs) are an important group of enzymes that determine the chiralities of the carbon backbones. SiaM is a special member of this group that can recognize substrates with different lengths and can be used iteratively. Here we report the crystal struc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Hua, Zhang, Huaidong, Zou, Yi, Mi, Yanling, Lin, Shuangjun, Xie, Zhixiong, Yan, Yunjun, Zhang, Houjin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046962/
https://ncbi.nlm.nih.gov/pubmed/24901639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097996
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