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The Effects of Codon Context on In Vivo Translation Speed

We developed a bacterial genetic system based on translation of the his operon leader peptide gene to determine the relative speed at which the ribosome reads single or multiple codons in vivo. Low frequency effects of so-called “silent” codon changes and codon neighbor (context) effects could be me...

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Detalhes bibliográficos
Main Authors: Chevance, Fabienne F. V., Le Guyon, Soazig, Hughes, Kelly T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046918/
https://ncbi.nlm.nih.gov/pubmed/24901308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004392
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