Co-chemoprevention of Mouse Lung Tumors by SAHA and Atorvastatin

Atorvastatin and SAHA were evaluated for co-chemoprevention of mouse lung tumors. In Experiment 1, lung tumors were induced by vinyl carbamate in strain A/J mice followed by 500 mg/kg SAHA, 60 or 180 mg/kg Atorvastatin, and combinations containing SAHA and Atorvastatin administered in their diet. SA...

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Bibliographic Details
Main Authors: Pereira, Michael A., Warner, Blake M., Knobloch, Thomas J., Weghorst, Christopher M., Lubet, Ronald A., Steele, Vernon E., Casto, Bruce C.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046909/
https://ncbi.nlm.nih.gov/pubmed/22161747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27395
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