Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria

Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of antibiotic targets caused by starvation-induced growth arrest is thought to be a key mechanism producing tolerance (1). Here we show that the antibiotic tolerance of nutrient-limited and biofilm Pseudomonas...

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Hlavní autoři: Nguyen, Dao, Joshi-Datar, Amruta, Lepine, Francois, Bauerle, Elizabeth, Olakanmi, Oyebode, Beer, Karlyn, McKay, Geoffrey, Siehnel, Richard, Schafhauser, James, Wang, Yun, Britigan, Bradley E., Singh, Pradeep K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046891/
https://ncbi.nlm.nih.gov/pubmed/22096200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1211037
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