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Localization of denaturation bubbles in random DNA sequences

We study the thermodynamic and dynamic behaviors of twist-induced denaturation bubbles in a long, stretched random sequence of DNA. The small bubbles associated with weak twist are delocalized. Above a threshold torque, the bubbles of several tens of bases or larger become preferentially localized t...

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Bibliografiske detaljer
Main Authors: Hwa, Terence, Marinari, Enzo, Sneppen, Kim, Tang, Lei-han
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404689/
https://ncbi.nlm.nih.gov/pubmed/12672955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736291100
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