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Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion

While inhibition of class I/IIb histone deacetylases (HDACs) protects the mammalian heart from ischemia reperfusion (IR) injury, class selective effects remain unexamined. We hypothesized that selective inhibition of class I HDACs would preserve left ventricular contractile function following IR in...

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Detalhes bibliográficos
Main Authors: Aune, Sverre E., Herr, Daniel J., Mani, Santhosh K., Menick, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046340/
https://ncbi.nlm.nih.gov/pubmed/24632412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.03.005
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