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TLR-4-Dependent and -Independent Mechanisms of Fetal Brain Injury in the Setting of Preterm Birth

In this study, we sought to assess how essential activation of toll-like receptor 4 (TLR-4) is to fetal brain injury from intrauterine inflammation. Both wild-type and TLR-4 mutant fetal central nervous system cells were exposed to inflammation using lipopolysaccharide in vivo or in vitro. Inflammat...

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Main Authors: Breen, Kelsey, Brown, Amy, Burd, Irina, Chai, Jinghua, Friedman, Alexander, Elovitz, Michal A.
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046308/
https://ncbi.nlm.nih.gov/pubmed/22825738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112438439
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