Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa

BACKGROUND: Tenofovir disoproxil fumarate (TDF) is increasingly available for patients infected with subtype C HIV-1. This subtype is reported to develop the principle TDF resistance mutation in the HIV reverse transcriptase, K65R, with greater propensity than other subtypes. We sought to describe K...

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Autori principali: Hoffmann, Christopher J, Ledwaba, Johanna, Li, Jin-fen, Johnston, Victoria, Hunt, Gillian, Fielding, Katherine L, Chaisson, Richard E, Churchyard, Gavin J, Grant, Alison D, Johnson, Jeffrey A, Charalambous, Salome, Morris, Lynn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046272/
https://ncbi.nlm.nih.gov/pubmed/23751421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2652
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