Follistatin Operates Downstream of Wnt4 in Mammalian Ovary Organogenesis

Wnt4(−/−) XX gonads display features normally associated with testis differentiation, suggesting that WNT4 actively represses elements of the male pathway during ovarian development. Here, we show that follistatin (Fst), which encodes a TGFβ superfamily binding protein, is a downstream component of...

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Autors principals: Yao, Humphrey H.C., Matzuk, Martin M., Jorgez, Carolina J., Menke, Douglas B., Page, David C., Swain, Amanda, Capel, Blanche
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046253/
https://ncbi.nlm.nih.gov/pubmed/15162500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20042
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