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Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation

Exercise substantially improves metabolic health, making the elicited mechanisms important targets for novel therapeutic strategies. Uncoupling protein 3 (UCP3) is a mitochondrial inner membrane protein highly selectively expressed in skeletal muscle. Here we report that moderate UCP3 overexpression...

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Bibliographische Detailangaben
Hauptverfasser: Aguer, Céline, Fiehn, Oliver, Seifert, Erin L., Bézaire, Véronic, Meissen, John K., Daniels, Amanda, Scott, Kyle, Renaud, Jean-Marc, Padilla, Marta, Bickel, David R., Dysart, Michael, Adams, Sean H., Harper, Mary-Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046190/
https://ncbi.nlm.nih.gov/pubmed/23825224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-234302
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