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Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.

A family of interferon (IFN) regulatory factors (IRFs) have been shown to play a role in transcription of IFN genes as well as IFN-stimulated genes. We report the identification of a member of the IRF family which we have named IRF-3. The IRF-3 gene is present in a single copy in human genomic DNA....

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Au, W C, Moore, P A, Lowther, W, Juang, Y T, Pitha, P M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1995
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11657
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