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Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala
Recently discovered neuropeptide S (NPS) has anxiolytic and pain-inhibiting effects in rodents. We showed previously that NPS increases synaptic inhibition of amygdala output to inhibit pain behaviors. The amygdala plays a key role in emotional-affective aspects of pain. Of clinical significance is...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046088/ https://ncbi.nlm.nih.gov/pubmed/24884567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-32 |
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