Enhanced Surfactant Protein and Defensin mRNA Levels and Reduced Viral Replication during Parainfluenza Virus Type 3 Pneumonia in Neonatal Lambs

Defensins and surfactant protein A (SP-A) and SP-D are antimicrobial components of the pulmonary innate immune system. The purpose of this study was to determine the extent to which parainfluenza type 3 virus infection in neonatal lambs alters expression of sheep beta-defensin 1 (SBD-1), SP-A, and S...

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Hlavní autoři: Grubor, Branka, Gallup, Jack M., Meyerholz, David K., Crouch, Erika C., Evans, Richard B., Brogden, Kim A., Lehmkuhl, Howard D., Ackermann, Mark R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Microbial Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC404576/
https://ncbi.nlm.nih.gov/pubmed/15138188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.3.599-607.2004
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