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Effects of Angiopoietin-1 on Hemorrhagic Transformation and Cerebral Edema after Tissue Plasminogen Activator Treatment for Ischemic Stroke in Rats

An angiogenesis factor, angiopoietin-1 (Ang1), is associated with the blood-brain barrier (BBB) disruption after focal cerebral ischemia. However, whether hemorrhagic transformation and cerebral edema after tissue plasminogen activator (tPA) treatment are related to the decrease in Ang1 expression i...

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Détails bibliographiques
Auteurs principaux: Kawamura, Kunio, Takahashi, Tetsuya, Kanazawa, Masato, Igarashi, Hironaka, Nakada, Tsutomu, Nishizawa, Masatoyo, Shimohata, Takayoshi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045756/
https://ncbi.nlm.nih.gov/pubmed/24896569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098639
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