A carregar...

Inhibitor Ranking through QM Based Chelation Calculations for Virtual Screening of HIV-1 RNase H Inhibition

Quantum mechanical (QM) calculations have been used to predict the binding affinity of a set of ligands towards HIV-1 RT associated RNase H (RNH). The QM based chelation calculations show improved binding affinity prediction for the inhibitors compared to using an empirical scoring function. Further...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Poongavanam, Vasanthanathan, Steinmann, Casper, Kongsted, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045755/
https://ncbi.nlm.nih.gov/pubmed/24897431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098659
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!