Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a highly diverse group that is associated with an aggressive phenotype. Its treatment has been challenging due to its heterogeneity and absence of well-defined molecular targets. Thus, there is an urgent need to identify novel agents with therapeut...

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Detalhes bibliográficos
Main Authors: Arora, Ritu, Yates, Clayton, Gary, Bernard D., McClellan, Steven, Tan, Ming, Xi, Yaguang, Reed, Eddie, Piazza, Gary A., Owen, Laurie B., Dean-Colomb, Windy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045585/
https://ncbi.nlm.nih.gov/pubmed/24896091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098370
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