Hydrogen Sulfide Releasing Aspirin, ACS14, Attenuates High Glucose-Induced Increased Methylglyoxal and Oxidative Stress in Cultured Vascular Smooth Muscle Cells

Hydrogen sulfide is a gasotransmitter with vasodilatory and anti-inflammatory properties. Aspirin is an irreversible cyclooxygenase inhibitor anti-inflammatory drug. ACS14 is a novel synthetic hydrogen sulfide releasing aspirin which inhibits cyclooxygenase and has antioxidant effects. Methylglyoxal...

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Bibliographic Details
Main Authors: Huang, Qian, Sparatore, Anna, Del Soldato, Piero, Wu, Lingyun, Desai, Kaushik
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045575/
https://ncbi.nlm.nih.gov/pubmed/24896242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097315
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