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MUC1: A Novel Metabolic Master Regulator
MUC1, a type I transmembrane protein, is significantly overexpressed and aberrantly glycosylated in tumors of epithelial origin. By virtue of its aberrant signaling due to loss of apical-basal polarity in cancer, MUC1 regulates the metabolite flux at multiple levels. Serving as a transcriptional co-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4045475/ https://ncbi.nlm.nih.gov/pubmed/24418575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2014.01.001 |
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