Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers

BACKGROUND: MicroRNAs are associated with tumor genesis and progression in various carcinomas. MicroRNA-148a (miR-148a) was reported to have low expression in gastrointestinal cancers, and might be regulated by promoter region DNA methylation. METHODS: Bisulfite-modified sequencing was used to deter...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sun, Jingxu, Song, Yongxi, Wang, Zhenning, Wang, Guoli, Gao, Peng, Chen, Xiaowan, Gao, Zhaohua, Xu, Huimian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045258/
https://ncbi.nlm.nih.gov/pubmed/24920927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S60888
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