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Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis.

Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, as well as for their maintenance in the adult. Homeobox genes comprise an important family of transcription factors, which are characterized by a well conserved DNA binding motif; the homeodomain. The...

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Autores principales: Murthi, Padma, Abumaree, Mohamed, Kalionis, Bill
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045154/
https://ncbi.nlm.nih.gov/pubmed/24926269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00133
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