In vivo immunogenicity of Tax 11-19 epitope in HLA-A2/DTR transgenic mice: implication for dendritic cell-based anti-HTLV-1 vaccine

Viral oncoprotein Tax plays key roles in transformation of human T-cell leukemia virus (HTLV-1)-infected T cells leading to adult T-cell leukemia (ATL), and is the key antigen recognized during HTLV-associated myelopathy (HAM). In HLA-A2+ asymptomatic carriers as well as ATL and HAM patients, Tax(11...

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Detalhes bibliográficos
Main Authors: Sagar, Divya, Masih, Shet, Schell, Todd, Jacobson, Steven, Comber, Joseph D., Philip, Ramila, Wigdahl, Brian, Jain, Pooja, Khan, Zafar K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044917/
https://ncbi.nlm.nih.gov/pubmed/24739247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.03.087
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