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Highly precise protein-protein interaction prediction based on consensus between template-based and de novo docking methods

BACKGROUND: Elucidation of protein-protein interaction (PPI) networks is important for understanding disease mechanisms and for drug discovery. Tertiary-structure-based in silico PPI prediction methods have been developed with two typical approaches: a method based on template matching with known pr...

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Bibliografske podrobnosti
Main Authors: Ohue, Masahito, Matsuzaki, Yuri, Shimoda, Takehiro, Ishida, Takashi, Akiyama, Yutaka
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044902/
https://ncbi.nlm.nih.gov/pubmed/24564962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-7-S7-S6
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