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Endothelin-1 Activation of the Endothelin B Receptor Modulates Pulmonary Endothelial CX3CL1 and Contributes to Pulmonary Angiogenesis in Experimental Hepatopulmonary Syndrome

Hepatic production and release of endothelin-1 (ET-1) binding to endothelin B (ET(B)) receptors, overexpressed in the lung microvasculature, is associated with accumulation of pro-angiogenic monocytes and vascular remodeling in experimental hepatopulmonary syndrome (HPS) after common bile duct ligat...

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Detalhes bibliográficos
Main Authors: Zhang, Junlan, Yang, Wenli, Hu, Bingqian, Wu, Wei, Fallon, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044720/
https://ncbi.nlm.nih.gov/pubmed/24731444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.02.027
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