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Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids

BACKGROUND: Multidrug resistance (MDR) is a phenomenon that is often associated with decreased intracellular drug accumulation in patient's tumor cells resulting from enhanced drug efflux. It is related to the overexpression of a membrane protein, P-glycoprotein (Pgp-170), thereby reducing drug...

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Sonraí Bibleagrafaíochta
Main Authors: Limtrakul, Pornngarm, Anuchapreeda, Songyot, Buddhasukh, Duang
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2004
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC404465/
https://ncbi.nlm.nih.gov/pubmed/15090070
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