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Length Quantization of DNA Partially Expelled from Heads of a Bacteriophage T3 Mutant

DNA packaging of phages phi29, T3 and T7 sometimes produces incompletely packaged DNA with quantized lengths, based on gel electrophoretic band formation. We discover here a packaging ATPase-free, in vitro model for packaged DNA length quantization. We use directed evolution to isolate a five-site T...

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Detalhes bibliográficos
Main Authors: Serwer, Philip, Wright, Elena T., Liu, Zheng, Jiang, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044629/
https://ncbi.nlm.nih.gov/pubmed/24889235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.03.016
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