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Impact of subthreshold membrane potential on synaptic responses at dendritic spines of layer 5 pyramidal neurons in the prefrontal cortex

Glutamatergic inputs onto cortical pyramidal neurons are received and initially processed at dendritic spines. AMPA and NMDA receptors generate both synaptic potentials and calcium (Ca) signals in the spine head. These responses can in turn activate a variety of Ca, sodium (Na), and potassium (K) ch...

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Главные авторы: Seong, Hannah J., Behnia, Rudy, Carter, Adam G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044337/
https://ncbi.nlm.nih.gov/pubmed/24478153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00590.2013
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