PReS-FINAL-2181: Recombinant il-1ra restores the il-18-nk cell axis in steroid naive systemic juvenile idiopathic arthritis

Eitemau Tebyg

• Akinra restores the defective IL-18 NK cell axis in steroid naïve systemic onset JIA patients
  gan: de Jager, W, et al.
  Cyhoeddwyd: (2011)
• Recombinant IL1-RA in the early phase of systemic onset JIA: before the onset of arthritis
  gan: Vastert, SJ, et al.
  Cyhoeddwyd: (2011)
• 4.5 Defective phosphorylation of the interleukin 18 receptor beta-chain causes impaired NK cell function in systemic onset Juvenile Idiopathic Arthritis
  gan: de Jager, W, et al.
  Cyhoeddwyd: (2008)
• PReS-FINAL-2342: Anti-TNFALPHA therapy targeys PKB/C-AKT induced resistance of effector cells to suppression in juvenile arthritis
  gan: Wehrens, E, et al.
  Cyhoeddwyd: (2013)
• PReS-FINAL-1019: Inflammatory monocytes induce resistance of effector t cells to suppression
  gan: Wehrens, EJ, et al.
  Cyhoeddwyd: (2013)