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Bacteriophage-Based Genetic System for Selection of Nonsplicing Inteins

A genetic selection system that detects splicing and nonsplicing activities of inteins was developed based on the ability to rescue a T4 phage strain with a conditionally inactive DNA polymerase. This phage defect can be complemented by expression of plasmid-encoded phage RB69 DNA polymerase. Insert...

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Bibliografiske detaljer
Main Authors: Cann, Isaac K. O., Amaya, Kensey R., Southworth, Maurice W., Perler, Francine B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404401/
https://ncbi.nlm.nih.gov/pubmed/15128583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.3158-3162.2004
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