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Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity
TLR2 plays a critical role in the protection against Paracoccidioides brasiliensis conferred by ArtinM administration. ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus, induces IL-12 production in macrophages and dendritic cells, which accounts for the T helper1 immunity that results...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043963/ https://ncbi.nlm.nih.gov/pubmed/24892697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098512 |
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