Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity

TLR2 plays a critical role in the protection against Paracoccidioides brasiliensis conferred by ArtinM administration. ArtinM, a D-mannose-binding lectin from Artocarpus heterophyllus, induces IL-12 production in macrophages and dendritic cells, which accounts for the T helper1 immunity that results...

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Autors principals: Mariano, Vania Sammartino, Zorzetto-Fernandes, Andre Luiz, da Silva, Thiago Aparecido, Ruas, Luciana Pereira, Nohara, Lilian L., de Almeida, Igor Correia, Roque-Barreira, Maria Cristina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043963/
https://ncbi.nlm.nih.gov/pubmed/24892697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098512
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