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Inhibitory Effect of a Callophycin A Derivative on iNOS Expression via Inhibition of Akt in Lipopolysaccharide-stimulated RAW 264.7 Cells

In previous studies, (R)-2-isobutyl 3-methyl 3,4-dihydro-1H-pyrido[3,4-b] indole-2,3(9H)-dicarboxylate (1), a callophycin A derivative, was found to strongly inhibit nitrite production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, while (R)- or (S)-callophycin A showed only weak inhibition...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, Eun-Jung, Shen, Li, Sun, Dianqing, Pezzuto, John M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043953/
https://ncbi.nlm.nih.gov/pubmed/24299616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400800h
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