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Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma

BACKGROUND: Tumor cells before and after epidermal growth-factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) therapy might display different characteristics. The aim of this study was to evaluate the influence of prior EGFR TKI therapy on the efficacy of subsequent pemetrexed plus platinum (PP)...

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Autors principals: Tseng, Jeng-Sen, Yang, Tsung-Ying, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Yu, Chong-Jen, Liao, Wei-Yu, Tsai, Chi-Ren, Tsai, Meen-Hsin, Yu, Sung-Liang, Su, Kang-Yi, Chen, Jeremy JW, Chen, Hsuan-Yu, Chang, Gee-Chen
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043805/
https://ncbi.nlm.nih.gov/pubmed/24920920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S62639
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