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Independent of Their Localization in Protein the Hydrophobic Amino Acid Residues Have No Effect on the Molten Globule State of Apomyoglobin and the Disulfide Bond on the Surface of Apomyoglobin Stabilizes This Intermediate State

At present it is unclear which interactions in proteins reveal the presence of intermediate states, their stability and formation rate. In this study, we have investigated the effect of substitutions of hydrophobic amino acid residues in the hydrophobic core of protein and on its surface on a molten...

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Autors principals: Melnik, Tatiana N., Majorina, Maria A., Larina, Daria S., Kashparov, Ivan A., Samatova, Ekaterina N., Glukhov, Anatoly S., Melnik, Bogdan S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043776/
https://ncbi.nlm.nih.gov/pubmed/24892675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098645
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