Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse

Intervertebral discs (IVDs) are strong fibrocartilaginous joints that connect adjacent vertebrae of the spine. As discs age they become prone to failure, with neurological consequences that are often severe. Surgical repair of discs treats the result of the disease, which affects as many as one in s...

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Bibliografiska uppgifter
Huvudupphovsmän: Winkler, Tamara, Mahoney, Eric J., Sinner, Debora, Wylie, Christopher C., Dahia, Chitra Lekha
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043533/
https://ncbi.nlm.nih.gov/pubmed/24892825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098444
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