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Primary Cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool
Cerebellar granule cell precursors (GCPs), which give rise to the most abundant neuronal type in the mammalian brain, arise from a restricted pool of primary progenitors in the rhombic lip (RL). Sonic hedgehog (Shh) secreted by developing Purkinje cells is essential for the expansion of GCPs and for...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043448/ https://ncbi.nlm.nih.gov/pubmed/18353302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.026 |
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