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Genes and environment: effects on the development of second malignancies in retinoblastoma survivors

Although it is a rare cancer, retinoblastoma has served as an important model in our understanding of genetic cancer syndromes. All patients with a germinal rb1 mutation possess a risk of the development of second malignancies. Approximately 40-50% of all retinoblastoma cases are considered germinal...

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Autori principali: Schefler, Amy C, Kleinerman, Ruth A, Abramson, David H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043380/
https://ncbi.nlm.nih.gov/pubmed/24904684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17469899.3.1.51
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