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Genomic mutation rates that neutralize adaptive evolution and natural selection

When mutation rates are low, natural selection remains effective, and increasing the mutation rate can give rise to an increase in adaptation rate. When mutation rates are high to begin with, however, increasing the mutation rate may have a detrimental effect because of the overwhelming presence of...

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Detalhes bibliográficos
Main Authors: Gerrish, Philip J., Colato, Alexandre, Sniegowski, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043167/
https://ncbi.nlm.nih.gov/pubmed/23720539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.0329
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