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GdDO3NI, a nitroimidazole-based T(1) MR contrast agent for imaging tumor hypoxia in vivo

Tumor hypoxia is known to affect sensitivity to radiotherapy and promote development of metastases. Therefore the ability to image tumor hypoxia in vivo could provide useful prognostic information and help tailor therapy. We previously demonstrated in vitro evidence for selective accumulation of GdD...

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Detalhes bibliográficos
Main Authors: Gulaka, Praveen K., Rojas-Quijano, Federico, Kovacs, Zoltan, Mason, Ralph P., Sherry, A. Dean, Kodibagkar, Vikram D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043141/
https://ncbi.nlm.nih.gov/pubmed/24281854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-1058-5
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