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Isolation of virus-neutralizing RNAs from a large pool of random sequences.

RNA and ribonuclease-resistant RNA analogs that bound and neutralized Rous sarcoma virus (RSV) were isolated from a large pool of random sequences by multiple cycles of in vitro selection using infectious viral particles. The selected RNA pool of RSV-binding sequences at a concentration of 0.16 micr...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Pan, W, Craven, R C, Qiu, Q, Wilson, C B, Wills, J W, Golovine, S, Wang, J F
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1995
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11509
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