Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-Å x-ray data

The R2 protein of class I ribonucleotide reductase generates and stores a tyrosyl radical essential for ribonucleotide reduction and, thus, DNA synthesis. X-ray structures of the protein have enabled detailed mechanistic suggestions, but no structural information has been available for the active ra...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Högbom, Martin, Galander, Marcus, Andersson, Martin, Kolberg, Matthias, Hofbauer, Wulf, Lassmann, Günter, Nordlund, Pär, Lendzian, Friedhelm
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12624184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0536684100
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