Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the transcription cycle and various steps of mRNA matura...

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Hlavní autoři: Descostes, Nicolas, Heidemann, Martin, Spinelli, Lionel, Schüller, Roland, Maqbool, Muhammad Ahmad, Fenouil, Romain, Koch, Frederic, Innocenti, Charlène, Gut, Marta, Gut, Ivo, Eick, Dirk, Andrau, Jean-Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
Genes and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042876/
https://ncbi.nlm.nih.gov/pubmed/24842994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02105
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