Tenofovir Diphosphate and Emtricitabine Triphosphate Concentrations in Blood Cells Compared with Isolated Peripheral Blood Mononuclear Cells: A New Measure of Antiretroviral Adherence?

BACKGROUND: The active metabolites of tenofovir (TFV) and emtricitabine (FTC) in peripheral blood mononuclear cells (PBMCs) have been used as markers of long-term antiretroviral (ARV) adherence. However, the process of isolating PBMCs is expensive, complex, and not feasible in many settings. We comp...

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Main Authors: Adams, Jessica L., Sykes, Craig, Menezes, Prema, Prince, Heather M.A., Patterson, Kristine B., Fransen, Katrien, Crucitti, Tania, De Baetselier, Irith, Van Damme, Lut, Kashuba, Angela D.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042836/
https://ncbi.nlm.nih.gov/pubmed/23111578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3182794723
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