Simplified Microarray System for Simultaneously Detecting Rifampin, Isoniazid, Ethambutol, and Streptomycin Resistance Markers in Mycobacterium tuberculosis

We developed a simplified microarray test for detecting and identifying mutations in rpoB, katG, inhA, embB, and rpsL and compared the analytical performance of the test to that of phenotypic drug susceptibility testing (DST). The analytical sensitivity was estimated to be at least 110 genome copies...

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Autors principals: Linger, Yvonne, Kukhtin, Alexander, Golova, Julia, Perov, Alexander, Lambarqui, Amine, Bryant, Lexi, Rudy, George B., Dionne, Kim, Fisher, Stefanie L., Parrish, Nicole, Chandler, Darrell P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042730/
https://ncbi.nlm.nih.gov/pubmed/24719444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00238-14
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