B lymphocytes undergo TLR2-dependent apoptosis upon Shigella infection

Antibody-mediated immunity to Shigella, the causative agent of bacillary dysentery, requires several episodes of infection to get primed and is short-lasting, suggesting that the B cell response is functionally impaired. We show that upon ex vivo infection of human colonic tissue, invasive S. flexne...

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Detalhes bibliográficos
Main Authors: Nothelfer, Katharina, Arena, Ellen T., Pinaud, Laurie, Neunlist, Michel, Mozeleski, Brian, Belotserkovsky, Ilia, Parsot, Claude, Dinadayala, Premkumar, Burger-Kentischer, Anke, Raqib, Rubhana, Sansonetti, Philippe J., Phalipon, Armelle
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042640/
https://ncbi.nlm.nih.gov/pubmed/24863068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130914
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