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Counter-regulation of T cell effector function by differentially activated p38

Unlike the MAP kinase (MAPK) cascade that phosphorylates p38 on the activation loop, T cell receptor (TCR) signaling results in phosphorylation on Tyr-323 (pY323, alternative pathway). Using mice expressing p38α and p38β with Y323F substitutions, we show that alternatively but not MAPK cascade-activ...

詳細記述

保存先:
書誌詳細
主要な著者: Alam, Muhammad S., Gaida, Matthias M., Ogawa, Youichi, Kolios, Antonios G.A., Lasitschka, Felix, Ashwell, Jonathan D.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042639/
https://ncbi.nlm.nih.gov/pubmed/24863062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131917
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