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In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate promotes local adipose and systemic inflammation in adult male offspring

BACKGROUND: Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer used to increase the flexibility of polyvinyl chloride. DEHP and its active metabolite mono-(2-ethylhexyl) phthalate are detected in many biological fluids during fetal and postnatal life. In rodent models, in utero DEHP exposure has be...

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Detalhes bibliográficos
Main Authors: Campioli, E, Martinez-Arguelles, D B, Papadopoulos, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042311/
https://ncbi.nlm.nih.gov/pubmed/24799162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2014.13
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