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Neuronostatin inhibits glucose-stimulated insulin secretion via direct action on the pancreatic α-cell

Neuronostatin is a recently described peptide hormone encoded by the somatostatin gene. We previously showed that intraperitoneal injection of neuronostatin into mice resulted in c-Jun accumulation in pancreatic islets in a pattern consistent with the activation of glucagon-producing α-cells. We the...

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Autori principali: Salvatori, Alison S., Elrick, Mollisa M., Samson, Willis K., Corbett, John A., Yosten, Gina L. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042099/
https://ncbi.nlm.nih.gov/pubmed/24735892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00599.2013
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