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Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system

The physiology of the vasculature in the central nervous system (CNS), which includes the blood-brain barrier (BBB) and other factors, complicates the delivery of most drugs to the brain. Different methods have been used to bypass the BBB, but they have limitations such as being invasive, non-target...

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Detalhes bibliográficos
Main Authors: Aryal, Muna, Arvanitis, Costas D., Alexander, Phillip M., McDannold, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041837/
https://ncbi.nlm.nih.gov/pubmed/24462453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.01.008
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