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Human Umbilical Cord-Derived Mesenchymal Stem Cells Do Not Undergo Malignant Transformation during Long-Term Culturing in Serum-Free Medium

BACKGROUND: Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are in the foreground as a preferable application for treating diseases. However, the safety of hUC-MSCs after long-term culturing in vitro in serum-free medium remains unclear. METHODS: hUC-MSCs were separated by adherent ti...

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Detalhes bibliográficos
Main Authors: Chen, Gecai, Yue, Aihuan, Ruan, Zhongbao, Yin, Yigang, Wang, RuZhu, Ren, Yin, Zhu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041760/
https://ncbi.nlm.nih.gov/pubmed/24887492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098565
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